About 1 result found for searched term "WRG-28 " (0.125 seconds)
Cat.No. | Name | Target |
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M29014 | WRG-28 | Discoidin Domain Receptor |
WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor, with an IC50 of 230 nM. WRG-28 inhibits tumor invasion, migration and tumor-supporting effects of cancer-associated fibroblasts (CAFs). WRG-28 inhibits metastatic breast tumor cell colonization in the lungs. WRG-28 also shows good activity of relieving rheumatoid arthritis in CAIA model of mice. |
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